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PDMP induces rapid changes in vacuole morphology in Arabidopsis root cells

PDMP (d-l-threo-1-phenyl-2-decanoyl amino-3-morpholino-1-propanol) is a well-known inhibitor of glucosylceramide synthase (GCS), a key enzyme in sphingolipid biosynthesis. Through the resultant increase in ceramides which interact with mTOR and Beclin1 (Atg6), this drug is also known to induce macro...

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Detalles Bibliográficos
Autores principales: Krüger, Falco, Krebs, Melanie, Viotti, Corrado, Langhans, Markus, Schumacher, Karin, Robinson, David G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542044/
https://www.ncbi.nlm.nih.gov/pubmed/23230024
http://dx.doi.org/10.1093/jxb/ers345