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A phenyl-thiadiazolylidene-amine derivative ejects zinc from retroviral nucleocapsid zinc fingers and inactivates HIV virions

BACKGROUND: Sexual acquisition of the human immunodeficiency virus (HIV) through mucosal transmission may be prevented by using topically applied agents that block HIV transmission from one individual to another. Therefore, virucidal agents that inactivate HIV virions may be used as a component in t...

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Detalles Bibliográficos
Autores principales: Vercruysse, Thomas, Basta, Beata, Dehaen, Wim, Humbert, Nicolas, Balzarini, Jan, Debaene, François, Sanglier-Cianférani, Sarah, Pannecouque, Christophe, Mély, Yves, Daelemans, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542062/
https://www.ncbi.nlm.nih.gov/pubmed/23146561
http://dx.doi.org/10.1186/1742-4690-9-95