Granzyme A Produced by γ(9)δ(2) T Cells Induces Human Macrophages to Inhibit Growth of an Intracellular Pathogen

Human γ(9)δ(2) T cells potently inhibit pathogenic microbes, including intracellular mycobacteria, but the key inhibitory mechanism(s) involved have not been identified. We report a novel mechanism involving the inhibition of intracellular mycobacteria by soluble granzyme A. γ(9)δ(2) T cells produce...

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Detalles Bibliográficos
Autores principales: Spencer, Charles T., Abate, Getahun, Sakala, Isaac G., Xia, Mei, Truscott, Steven M., Eickhoff, Christopher S., Linn, Rebecca, Blazevic, Azra, Metkar, Sunil S., Peng, Guangyong, Froelich, Christopher J., Hoft, Daniel F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542113/
https://www.ncbi.nlm.nih.gov/pubmed/23326234
http://dx.doi.org/10.1371/journal.ppat.1003119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542113/
https://www.ncbi.nlm.nih.gov/pubmed/23326234
http://dx.doi.org/10.1371/journal.ppat.1003119

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