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Granzyme A Produced by γ(9)δ(2) T Cells Induces Human Macrophages to Inhibit Growth of an Intracellular Pathogen
Human γ(9)δ(2) T cells potently inhibit pathogenic microbes, including intracellular mycobacteria, but the key inhibitory mechanism(s) involved have not been identified. We report a novel mechanism involving the inhibition of intracellular mycobacteria by soluble granzyme A. γ(9)δ(2) T cells produce...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542113/ https://www.ncbi.nlm.nih.gov/pubmed/23326234 http://dx.doi.org/10.1371/journal.ppat.1003119 |