Assembly of Dishevelled 3-based supermolecular complexes via phosphorylation and Axin

BACKGROUND: Dishevelled-3 (Dvl3) is a multivalent scaffold essential to cell signaling in development. Dsh/Dvls enable a myriad of protein-protein interactions in Wnt signaling. In the canonical Wnt/β-catenin pathway specifically, Dvl3 polymerizes to form dynamic protein aggregates, so-called “signa...

Descripción completa

Detalles Bibliográficos
Autores principales: Yokoyama, Noriko, Markova, Nelli G, Wang, Hsien-yu, Malbon, Craig C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542119/
https://www.ncbi.nlm.nih.gov/pubmed/22748080
http://dx.doi.org/10.1186/1750-2187-7-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542119/
https://www.ncbi.nlm.nih.gov/pubmed/22748080
http://dx.doi.org/10.1186/1750-2187-7-8

Ejemplares similares