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Assembly of Dishevelled 3-based supermolecular complexes via phosphorylation and Axin
BACKGROUND: Dishevelled-3 (Dvl3) is a multivalent scaffold essential to cell signaling in development. Dsh/Dvls enable a myriad of protein-protein interactions in Wnt signaling. In the canonical Wnt/β-catenin pathway specifically, Dvl3 polymerizes to form dynamic protein aggregates, so-called “signa...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542119/ https://www.ncbi.nlm.nih.gov/pubmed/22748080 http://dx.doi.org/10.1186/1750-2187-7-8 |