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Evolution of the hepatitis E virus hypervariable region

The presence of a hypervariable (HVR) region within the genome of hepatitis E virus (HEV) remains unexplained. Previous studies have described the HVR as a proline-rich spacer between flanking functional domains of the ORF1 polyprotein. Others have proposed that the region has no function, that it r...

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Detalles Bibliográficos
Autores principales: Smith, Donald B., Vanek, Jeff, Ramalingam, Sandeep, Johannessen, Ingolfur, Templeton, Kate, Simmonds, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for General Microbiology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542125/
https://www.ncbi.nlm.nih.gov/pubmed/22837418
http://dx.doi.org/10.1099/vir.0.045351-0