Cargando…

Evolution of the hepatitis E virus hypervariable region

The presence of a hypervariable (HVR) region within the genome of hepatitis E virus (HEV) remains unexplained. Previous studies have described the HVR as a proline-rich spacer between flanking functional domains of the ORF1 polyprotein. Others have proposed that the region has no function, that it r...

Descripción completa

Detalles Bibliográficos
Autores principales:	Smith, Donald B., Vanek, Jeff, Ramalingam, Sandeep, Johannessen, Ingolfur, Templeton, Kate, Simmonds, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Society for General Microbiology 2012
Materias:	Animal
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542125/ https://www.ncbi.nlm.nih.gov/pubmed/22837418 http://dx.doi.org/10.1099/vir.0.045351-0

Ejemplares similares

Hepatitis E Virus Mixed Infection in Immunocompetent Patient
por: Smith, Donald B., et al.
Publicado: (2013)

Characterization of antibody-mediated neutralization directed against the hypervariable region 1 of hepatitis C virus E2 glycoprotein
por: Vieyres, Gabrielle, et al.
Publicado: (2011)

Proline-Rich Hypervariable Region of Hepatitis E Virus: Arranging the Disorder
por: Muñoz-Chimeno, Milagros, et al.
Publicado: (2020)

Hepatitis E virus is the leading cause of acute viral hepatitis in Lothian, Scotland
por: Kokki, I., et al.
Publicado: (2015)

An essential RNA element resides in a central region of hepatitis E virus ORF2
por: Emerson, Suzanne U., et al.
Publicado: (2013)

Ultradeep Pyrosequencing of Hepatitis C Virus Hypervariable Region 1 in Quasispecies Analysis
por: Caraballo Cortés, Kamila, et al.
Publicado: (2013)

Hepatitis E virus and fulminant hepatitis–a virus or host-specific pathology?
por: Smith, Donald B, et al.
Publicado: (2015)

Novel hepatitis E like virus found in Swedish moose
por: Lin, Jay, et al.
Publicado: (2014)

Role of the E2 Hypervariable Region (HVR1) in the Immunogenicity of a Recombinant Hepatitis C Virus Vaccine
por: Law, John L. M., et al.
Publicado: (2018)

Spouse-to-Spouse Transmission and Evolution of Hypervariable Region 1 and 5’ Untranslated Region of Hepatitis C Virus Analyzed by Next-Generation Sequencing
por: Caraballo Cortes, Kamila, et al.
Publicado: (2016)

Reduction of Cell Fusion by Deletion in the Hypervariable Region of the Spike Protein of Mouse Hepatitis Virus
por: Tennakoon, Nipuna, et al.
Publicado: (2022)

Characterization of self-assembled virus-like particles of rat hepatitis E virus generated by recombinant baculoviruses
por: Li, Tian-Cheng, et al.
Publicado: (2011)

Broadly neutralizing human monoclonal antibodies to the hepatitis C virus E2 glycoprotein
por: Owsianka, Ania M., et al.
Publicado: (2008)

The non-primate hepacivirus 5′ untranslated region possesses internal ribosomal entry site activity
por: Stewart, Hazel, et al.
Publicado: (2013)

In vitro adaptation and characterization of attenuated hypervariable region 1 swap chimeras of hepatitis C virus
por: Olesen, Christina Holmboe, et al.
Publicado: (2021)

Comprehensive linker-scanning mutagenesis of the hepatitis C virus E1 and E2 envelope glycoproteins reveals new structure–function relationships
por: Rychłowska, Małgorzata, et al.
Publicado: (2011)

Hepatitis C virus infection of cholangiocarcinoma cell lines
por: Fletcher, Nicola F., et al.
Publicado: (2015)

Detection of influenza C virus but not influenza D virus in Scottish respiratory samples
por: Smith, Donald B., et al.
Publicado: (2016)

Hepatitis C Virus Hypervariable Region 1 Variants Presented on Hepatitis B Virus Capsid-Like Particles Induce Cross-Neutralizing Antibodies
por: Lange, Milena, et al.
Publicado: (2014)

The use of human sewage screening for community surveillance of hepatitis E virus in the UK
por: Smith, Donald B., et al.
Publicado: (2015)

Virus Isolate‐specific Antibodies against Hypervariable Region 1 of the Hepatitis C Virus Second Envelope Protein, gp70
por: Kato, Nobuyuki, et al.
Publicado: (1994)

Eight novel hepatitis C virus genomes reveal the changing taxonomic structure of genotype 6
por: Wang, Hongren, et al.
Publicado: (2013)

Experimental confirmation of recombination upstream of the S1 hypervariable region of infectious bronchitis virus
por: Wang, Li, et al.
Publicado: (1997)

Permissivity of primary hepatocytes and hepatoma cell lines to support hepatitis C virus infection
por: Wilson, Garrick K., et al.
Publicado: (2015)

Hypervariability within the Rifin, Stevor and Pfmc-2TM superfamilies in Plasmodium falciparum
por: Lavazec, Catherine, et al.
Publicado: (2006)

High-Affinity Interaction of the K-Ras4B Hypervariable Region with the Ras Active Site
por: Chavan, Tanmay S., et al.
Publicado: (2015)

Consensus proposals for classification of the family Hepeviridae
por: Smith, Donald B., et al.
Publicado: (2014)

Sero-reactivity to three distinct regions within the hepatitis C virus alternative reading frame protein (ARFP/core+1) in patients with chronic HCV genotype-3 infection
por: Elsheikh, Mosaab E. A., et al.
Publicado: (2022)

Acidic residues in the membrane-proximal stalk region of vaccinia virus protein B5 are required for glycosaminoglycan-mediated disruption of the extracellular enveloped virus outer membrane
por: Roberts, Kim L., et al.
Publicado: (2009)

Inhibition of the RNA polymerase III-mediated dsDNA-sensing pathway of innate immunity by vaccinia virus protein E3
por: Valentine, Robert, et al.
Publicado: (2010)

Proposals for the classification of human rhinovirus species A, B and C into genotypically assigned types
por: McIntyre, Chloe L., et al.
Publicado: (2013)

The crystal structure of vaccinia virus protein E2 and perspectives on the prediction of novel viral protein folds
por: Gao, William N. D., et al.
Publicado: (2022)

Hepatitis E virus (HEV) in Scotland: evidence of recent increase in viral circulation in humans
por: Thom, Katrina, et al.
Publicado: (2018)

Molecular Epidemiology and Evolution of Human Respiratory Syncytial Virus and Human Metapneumovirus
por: Gaunt, Eleanor R., et al.
Publicado: (2011)

Effects of hypervariable regions in spike protein on pathogenicity, tropism, and serotypes of infectious bronchitis virus
por: Shan, Dan, et al.
Publicado: (2018)

Deep sequencing of hepatitis C virus hypervariable region 1 reveals no correlation between genetic heterogeneity and antiviral treatment outcome
por: Caraballo Cortés, Kamila, et al.
Publicado: (2014)

Hypervariable Region 1 in Envelope Protein 2 of Hepatitis C Virus: A Linchpin in Neutralizing Antibody Evasion and Viral Entry
por: Prentoe, Jannick, et al.
Publicado: (2018)

Polyvalent immunization elicits a synergistic broadly neutralizing immune response to hypervariable region 1 variants of hepatitis C virus
por: Mosa, Alexander I., et al.
Publicado: (2023)

Rapid evolution of the env gene leader sequence in cats naturally infected with feline immunodeficiency virus
por: Bęczkowski, Paweł M., et al.
Publicado: (2015)

Dimerization-driven interaction of hepatitis C virus core protein with NS3 helicase
por: Mousseau, G., et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_fu7tdj23337t0h9acmrm79a5fh