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Needle length control and the secretion substrate specificity switch are only loosely coupled in the type III secretion apparatus of Shigella

The type III secretion apparatus (T3SA), which is evolutionarily and structurally related to the bacterial flagellar hook basal body, is a key virulence factor used by many Gram-negative bacteria to inject effector proteins into host cells. A hollow extracellular needle forms the injection conduit o...

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Detalles Bibliográficos
Autores principales: Shen, Da-Kang, Moriya, Nao, Martinez-Argudo, Isabel, Blocker, Ariel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for General Microbiology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542141/
https://www.ncbi.nlm.nih.gov/pubmed/22575894
http://dx.doi.org/10.1099/mic.0.059618-0