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Activity of pemetrexed and high-dose gefitinib in an EGFR-mutated lung adenocarcinoma with brain and leptomeningeal metastasis after response to gefitinib

About 20% to 40% of patients with non-small cell lung cancer (NSCLC) will develop brain metastases during the natural course of their disease. The prognosis for such patients is very poor with limited survival. In addition to the standard whole brain radiation therapy (WBRT), some studies have shown...

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Detalles Bibliográficos
Autores principales: Yuan, Ying, Tan, Chunwen, Li, Modan, Shen, Hong, Fang, Xuefeng, Hu, Yinghong, Ma, Shenglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542167/
https://www.ncbi.nlm.nih.gov/pubmed/23134665
http://dx.doi.org/10.1186/1477-7819-10-235