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Genome-Wide Screens for In Vivo Tinman Binding Sites Identify Cardiac Enhancers with Diverse Functional Architectures

The NK homeodomain factor Tinman is a crucial regulator of early mesoderm patterning and, together with the GATA factor Pannier and the Dorsocross T-box factors, serves as one of the key cardiogenic factors during specification and differentiation of heart cells. Although the basic framework of regu...

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Detalles Bibliográficos
Autores principales: Jin, Hong, Stojnic, Robert, Adryan, Boris, Ozdemir, Anil, Stathopoulos, Angelike, Frasch, Manfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542182/
https://www.ncbi.nlm.nih.gov/pubmed/23326246
http://dx.doi.org/10.1371/journal.pgen.1003195