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X-radiation inhibits histone deacetylase 1 and 2, upregulates Axin expression and induces apoptosis in non-small cell lung cancer

BACKGROUND: Histone deacetylase (HDAC) plays an important role in the deacetylation of histone, which can alter gene expression patterns and affect cell behavior associated with malignant transformation. The aims of this study were to investigate the relationships between HDAC1, HDAC2, clinicopathol...

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Detalles Bibliográficos
Autores principales: Han, Yang, Zhang, Yong, Yang, Lian-he, Mi, Xiao-yi, Dai, Shun-dong, Li, Qing-chang, Xu, Hong-tao, Yu, Juan-han, Li, Guang, Zhao, Jing, Han, Chong, Yuan, Xi-ming, Wang, En-hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542190/
https://www.ncbi.nlm.nih.gov/pubmed/23110995
http://dx.doi.org/10.1186/1748-717X-7-183