Downregulation of the Mitochondrial Phosphatase PTPMT1 Is Sufficient to Promote Cancer Cell Death

Protein Tyrosine Phosphatase localized to the Mitochondrion 1 (PTPMT1) is a dual specificity phosphatase exclusively localized to the mitochondria, and has recently been shown to be a critical component in the cardiolipin biosynthetic pathway. The downregulation of PTPMT1 in pancreatic beta cells ha...

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Detalles Bibliográficos
Autores principales: Niemi, Natalie M., Lanning, Nathan J., Westrate, Laura M., MacKeigan, Jeffrey P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542197/
https://www.ncbi.nlm.nih.gov/pubmed/23326511
http://dx.doi.org/10.1371/journal.pone.0053803

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542197/
https://www.ncbi.nlm.nih.gov/pubmed/23326511
http://dx.doi.org/10.1371/journal.pone.0053803

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