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Downregulation of the Mitochondrial Phosphatase PTPMT1 Is Sufficient to Promote Cancer Cell Death
Protein Tyrosine Phosphatase localized to the Mitochondrion 1 (PTPMT1) is a dual specificity phosphatase exclusively localized to the mitochondria, and has recently been shown to be a critical component in the cardiolipin biosynthetic pathway. The downregulation of PTPMT1 in pancreatic beta cells ha...
Autores principales: | Niemi, Natalie M., Lanning, Nathan J., Westrate, Laura M., MacKeigan, Jeffrey P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542197/ https://www.ncbi.nlm.nih.gov/pubmed/23326511 http://dx.doi.org/10.1371/journal.pone.0053803 |
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