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Autophagy is differentially induced in prostate cancer LNCaP, DU145 and PC-3 cells via distinct splicing profiles of ATG5

Autophagic responses to chemotherapeutic agents may vary greatly among different prostate cancer cells and have not been well characterized. In this study, we showed that valproic acid (VPA) induced conversion of LC3-I to LC3-II and formation of LC3 puncta, the typical markers of autophagy, in LNCaP...

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Detalles Bibliográficos
Autores principales: Ouyang, Dong-Yun, Xu, Li-Hui, He, Xian-Hui, Zhang, Yan-Ting, Zeng, Long-Hui, Cai, Ji-Ye, Ren, Shuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542215/
https://www.ncbi.nlm.nih.gov/pubmed/23075929
http://dx.doi.org/10.4161/auto.22397