Sabiporide Improves Cardiovascular Function, Decreases the Inflammatory Response and Reduces Mortality in Acute Metabolic Acidosis in Pigs

INTRODUCTION: Acute metabolic acidosis impairs cardiovascular function and increases the mortality of critically ill patients. However, the precise mechanism(s) underlying these effects remain unclear. We hypothesized that targeting pH-regulatory protein, Na(+)/H(+) exchanger (NHE1) could be a novel...

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Detalles Bibliográficos
Autores principales: Wu, Dongmei, Kraut, Jeffrey A., Abraham, William M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542271/
https://www.ncbi.nlm.nih.gov/pubmed/23326542
http://dx.doi.org/10.1371/journal.pone.0053932

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542271/
https://www.ncbi.nlm.nih.gov/pubmed/23326542
http://dx.doi.org/10.1371/journal.pone.0053932

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