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Characterization of Growth Suppressive Functions of a Splice Variant of Cyclin D2

We have recently cloned a novel splice variant of cyclin D2 termed as cycD2SV. CycD2SV overexpression in several immortalized cell lines led to formation of ubiquitinated protein aggregates accompanied by a significant decrease in cell proliferation. Based on immuno co-localization and ultrastructur...

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Detalles Bibliográficos
Autores principales: Wafa, Karim, MacLean, Jessica, Zhang, Feixiong, Pasumarthi, Kishore B. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542336/
https://www.ncbi.nlm.nih.gov/pubmed/23326442
http://dx.doi.org/10.1371/journal.pone.0053503