Monomer DJ-1 and Its N-Terminal Sequence Are Necessary for Mitochondrial Localization of DJ-1 Mutants

DJ-1 is a novel oncogene and also a causative gene for familial Parkinson’s disease (park7). DJ-1 has multiple functions that include transcriptional regulation, anti-oxidative reaction and chaperone and mitochondrial regulation. Mitochondrial dysfunction is observed in DJ-1-knockout mice and fry, a...

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Detalles Bibliográficos
Autores principales: Maita, Chinatsu, Maita, Hiroshi, Iguchi-Ariga, Sanae M. M., Ariga, Hiroyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542337/
https://www.ncbi.nlm.nih.gov/pubmed/23326576
http://dx.doi.org/10.1371/journal.pone.0054087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542337/
https://www.ncbi.nlm.nih.gov/pubmed/23326576
http://dx.doi.org/10.1371/journal.pone.0054087

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