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Neonatal Plasmacytoid Dendritic Cells (pDCs) Display Subset Variation but Can Elicit Potent Anti-Viral Innate Responses

Neonates are highly susceptible to infectious diseases and defective antiviral pDC immune responses have been proposed to contribute to this phenomenon. Isolated cord blood pDCs innately responded to a variety of TLR7 and TLR9 dependent viruses, including influenza A virus (IAV), human immunodeficie...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaoming, Lepelley, Alice, Azria, Elie, Lebon, Pierre, Roguet, Gwenaelle, Schwartz, Olivier, Launay, Odile, Leclerc, Claude, Lo-Man, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542339/
https://www.ncbi.nlm.nih.gov/pubmed/23326320
http://dx.doi.org/10.1371/journal.pone.0052003