Functional Promoter -308G>A Variant in Tumor Necrosis Factor α Gene Is Associated with Risk and Progression of Gastric Cancer in a Chinese Population

BACKGROUND: Tumor necrosis factor-α (TNF-α) plays a crucial role in the development and progression of gastric cancer. A functional polymorphism, -308 G>A (rs1800629), which is located in the promoter of TNFA gene, has been suggested to alter the production of TNF-α and influence cancer risk. In...

Descripción completa

Detalles Bibliográficos
Autores principales: Hong, Yan, Ge, Zhijun, Jing, Changrui, Shi, Jun, Dong, Xiao, Zhou, Fengying, Wang, Meilin, Zhang, Zhengdong, Gong, Weida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542372/
https://www.ncbi.nlm.nih.gov/pubmed/23326309
http://dx.doi.org/10.1371/journal.pone.0050856

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542372/
https://www.ncbi.nlm.nih.gov/pubmed/23326309
http://dx.doi.org/10.1371/journal.pone.0050856

Ejemplares similares