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Functional Promoter -308G>A Variant in Tumor Necrosis Factor α Gene Is Associated with Risk and Progression of Gastric Cancer in a Chinese Population

BACKGROUND: Tumor necrosis factor-α (TNF-α) plays a crucial role in the development and progression of gastric cancer. A functional polymorphism, -308 G>A (rs1800629), which is located in the promoter of TNFA gene, has been suggested to alter the production of TNF-α and influence cancer risk. In...

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Detalles Bibliográficos
Autores principales:	Hong, Yan, Ge, Zhijun, Jing, Changrui, Shi, Jun, Dong, Xiao, Zhou, Fengying, Wang, Meilin, Zhang, Zhengdong, Gong, Weida
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542372/ https://www.ncbi.nlm.nih.gov/pubmed/23326309 http://dx.doi.org/10.1371/journal.pone.0050856

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