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Menin and GIP are inversely regulated by food intake and diet via PI3/AKT signaling in the proximal duodenum

BACKGROUND AND AIMS: Ingestion of food stimulates the secretion of incretin peptides glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide 1 to ensure the proper absorption and storage of nutrients. Menin is the 67 kDa protein product of the MEN1 gene recently reported to have...

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Detalles Bibliográficos
Autores principales: Angevine, K R, Wuescher, L M, Andrews, K, Alexander, L A, McInerney, M F, Kieffer, T J, Mensah-Osman, E J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542434/
https://www.ncbi.nlm.nih.gov/pubmed/23208416
http://dx.doi.org/10.1038/nutd.2012.30