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Menin and GIP are inversely regulated by food intake and diet via PI3/AKT signaling in the proximal duodenum
BACKGROUND AND AIMS: Ingestion of food stimulates the secretion of incretin peptides glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide 1 to ensure the proper absorption and storage of nutrients. Menin is the 67 kDa protein product of the MEN1 gene recently reported to have...
Autores principales: | Angevine, K R, Wuescher, L M, Andrews, K, Alexander, L A, McInerney, M F, Kieffer, T J, Mensah-Osman, E J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542434/ https://www.ncbi.nlm.nih.gov/pubmed/23208416 http://dx.doi.org/10.1038/nutd.2012.30 |
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