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The role of G protein coupled receptor kinases in neurocardiovascular pathophysiology

In coronary artery disease the G protein related kinases (GRKs) play a role in desensitization of β-adrenoreceptors (AR) after coronary occlusion. Targeted deletion and lowering of cardiac myocyte GRK-2 decreases the risk of post-ischemic heart failure (HF). Studies carried out in humans confirm the...

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Detalles Bibliográficos
Autores principales: Bojic, Tijana, Sudar, Emina, Mikhailidis, Dimitri, Alavantic, Dragan, Isenovic, Esma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542506/
https://www.ncbi.nlm.nih.gov/pubmed/23319968
http://dx.doi.org/10.5114/aoms.2012.29996