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FGFR-1 amplification in metastatic lymph-nodal and haematogenous lobular breast carcinoma

BACKGROUND: Lobular breast carcinoma usually shows poor responsiveness to chemotherapies and often lacks targeted therapies. Since FGFR1 expression has been shown to play pivotal roles in primary breast cancer tumorigenesis, we sought to analyze the status of FGFR1 gene in a metastatic setting of lo...

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Detalles Bibliográficos
Autores principales: Brunello, Eleonora, Brunelli, Matteo, Bogina, Giuseppe, Caliò, Anna, Manfrin, Erminia, Nottegar, Alessia, Vergine, Marco, Molino, Annamaria, Bria, Emilio, Massari, Francesco, Tortora, Giampaolo, Cingarlini, Sara, Pedron, Serena, Chilosi, Marco, Zamboni, Giuseppe, Miller, Keith, Martignoni, Guido, Bonetti, Franco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542523/
https://www.ncbi.nlm.nih.gov/pubmed/23270564
http://dx.doi.org/10.1186/1756-9966-31-103