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A mechanism for robust circadian timekeeping via stoichiometric balance

Circadian (∼24 h) timekeeping is essential for the lives of many organisms. To understand the biochemical mechanisms of this timekeeping, we have developed a detailed mathematical model of the mammalian circadian clock. Our model can accurately predict diverse experimental data including the phenoty...

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Detalles Bibliográficos
Autores principales: Kim, Jae Kyoung, Forger, Daniel B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542529/
https://www.ncbi.nlm.nih.gov/pubmed/23212247
http://dx.doi.org/10.1038/msb.2012.62