ABT-737 promotes tBid mitochondrial accumulation to enhance TRAIL-induced apoptosis in glioblastoma cells

To search for novel strategies to enhance the tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis pathways in glioblastoma, we used the B-cell lymphoma 2/Bcl2-like 2-inhibitor ABT-737. Here we report that ABT-737 and TRAIL cooperate to induce apoptosis in several gliobl...

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Detalles Bibliográficos
Autores principales: Cristofanon, S, Fulda, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542599/
https://www.ncbi.nlm.nih.gov/pubmed/23190604
http://dx.doi.org/10.1038/cddis.2012.163

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542599/
https://www.ncbi.nlm.nih.gov/pubmed/23190604
http://dx.doi.org/10.1038/cddis.2012.163

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