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Overexpression of Uromodulin-like1 accelerates follicle depletion and subsequent ovarian degeneration

Murine Uromodulin-like 1 (Umodl1) encodes Ca(2+)-dependent EGF-like membrane-bound proteins. This study presents its novel expression in the immune and female reproductive systems. Upon stimulation by CD3/CD28 antibodies, Umodl1 showed a prompt and robust response in the proliferating CD4(+) T cells...

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Detalles Bibliográficos
Autores principales: Wang, W, Tang, Y, Ni, L, Kim, E, Jongwutiwes, T, Hourvitz, A, Zhang, R, Xiong, H, Liu, H-C, Rosenwaks, Z
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542605/
https://www.ncbi.nlm.nih.gov/pubmed/23190605
http://dx.doi.org/10.1038/cddis.2012.169