uPAR and cathepsin B shRNA impedes TGF-β1-driven proliferation and invasion of meningioma cells in a XIAP-dependent pathway

Overexpression of transforming growth factor β1 (TGF-β1) has been linked to immune suppression, tumor angiogenesis, tumor cell migration, tumor cell survival, and tumor cell invasion in many cancers. In the present study, we found abundant expression of TGF-β1 in the microenvironment of four differe...

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Detalles Bibliográficos
Autores principales: Gogineni, V R, Gupta, R, Nalla, A K, Velpula, K K, Rao, J S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542612/
https://www.ncbi.nlm.nih.gov/pubmed/23222509
http://dx.doi.org/10.1038/cddis.2012.170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542612/
https://www.ncbi.nlm.nih.gov/pubmed/23222509
http://dx.doi.org/10.1038/cddis.2012.170

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