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Senescence-associated secretory phenotype favors the emergence of cancer stem-like cells

The molecular mechanisms underlying cancer resistance remain elusive. One possible explanation is that cancer stem cells (CSCs) elude drug treatment, emerge and reproduce a tumor. Using multiple myeloma as a paradigm, we showed that cancer stem-like cells (CSLCs) appear after genotoxic stress becaus...

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Detalles Bibliográficos
Autores principales: Cahu, J, Bustany, S, Sola, B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542619/
https://www.ncbi.nlm.nih.gov/pubmed/23254289
http://dx.doi.org/10.1038/cddis.2012.183