Grainyhead-like 2 (GRHL2) inhibits keratinocyte differentiation through epigenetic mechanism

We recently identified Grainyhead-like 2 (GRHL2), a mammalian homolog of Grainyhead in Drosophila, to be a novel transcription factor that regulates hTERT gene expression and enhances proliferation of normal human epidermal keratinocytes (NHEK). In the current study, we show that GRHL2 impairs kerat...

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Detalles Bibliográficos
Autores principales: Chen, W, Xiao Liu, Z, Oh, J-E, Shin, K-H, Kim, R H, Jiang, M, Park, N-H, Kang, M K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542624/
https://www.ncbi.nlm.nih.gov/pubmed/23254293
http://dx.doi.org/10.1038/cddis.2012.190

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542624/
https://www.ncbi.nlm.nih.gov/pubmed/23254293
http://dx.doi.org/10.1038/cddis.2012.190

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