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Prognostic utility of intact immunoglobulin Ig′κ/Ig′λ ratios in multiple myeloma patients

To determine whether isotype matched immunoglobulin (Ig; Ig′κ/Ig′λ) ratios had prognostic significance in patients with intact Ig multiple myeloma (MM). Novel immunoassays measuring serum concentrations of the Ig heavy chain/light chain (HLC) subsets IgGκ, IgGλ, IgAκ and IgAλ were compared with mono...

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Detalles Bibliográficos
Autores principales: Bradwell, A, Harding, S, Fourrier, N, Mathiot, C, Attal, M, Moreau, P, Harousseau, J-L, Avet-Loiseau, H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542628/
https://www.ncbi.nlm.nih.gov/pubmed/22699454
http://dx.doi.org/10.1038/leu.2012.159