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Seamless replacement of Autographa californica multiple nucleopolyhedrovirus gp64 with each of five novel type II alphabaculovirus fusion sequences generates pseudotyped virus that fails to transduce mammalian cells

Autographa californica multiple nucleopolyhedrovirus (AcMNPV), a member of the type I alphabaculoviruses, is able to transduce and deliver a functional gene to a range of non-host cells, including many mammalian lines and primary cells, a property mediated by the envelope fusion protein GP64. AcMNPV...

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Detalles Bibliográficos
Autores principales: Westenberg, Marcel, Soedling, Helen M., Hirani, Nisha, Nicholson, Linda J., Mann, Derek A., Dolphin, Colin T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for General Microbiology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542734/
https://www.ncbi.nlm.nih.gov/pubmed/22492915
http://dx.doi.org/10.1099/vir.0.041921-0