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The VMP1-Beclin 1 interaction regulates autophagy induction

The Vacuole Membrane Protein 1 -VMP1- is a pancreatitis-associated transmembrane protein whose expression triggers autophagy in several human diseases. In the current study, we unveil the mechanism through which this protein induces autophagosome formation in mammalian cells. We show that VMP1 autop...

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Detalles Bibliográficos
Autores principales: Molejon, Maria I., Ropolo, Alejandro, Re, Andrea Lo, Boggio, Veronica, Vaccaro, Maria I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542764/
https://www.ncbi.nlm.nih.gov/pubmed/23316280
http://dx.doi.org/10.1038/srep01055