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SOCS2 is dispensable for BCR/ABL1-induced chronic myeloid leukemia-like disease and for normal hematopoietic stem cell function

Suppressor of cytokine signaling 2 (SOCS2) is known as a feedback inhibitor of cytokine signaling and is highly expressed in primary bone marrow (BM) cells from patients with chronic myeloid leukemia (CML). However, it has not been established whether SOCS2 is involved in CML, caused by the BCR/ABL1...

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Detalles Bibliográficos
Autores principales: Hansen, N, Ågerstam, H, Wahlestedt, M, Landberg, N, Askmyr, M, Ehinger, M, Rissler, M, Lilljebjörn, H, Johnels, P, Ishiko, J, Melo, J V, Alexander, W S, Bryder, D, Järås, M, Fioretos, T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542906/
https://www.ncbi.nlm.nih.gov/pubmed/22824785
http://dx.doi.org/10.1038/leu.2012.169