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Disrupted erythropoietin signaling promotes obesity and alters hypothalamus proopiomelanocortin production

While erythropoietin is the cytokine known that regulates erythropoiesis, erythropoietin receptor (EpoR) expression and associated activity beyond hematopoietic tissue remain uncertain. Here we show that mice with EpoR expression restricted to hematopoietic tissues (Tg) develop obesity and insulin r...

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Detalles Bibliográficos
Autores principales: Teng, Ruifeng, Gavrilova, Oksana, Suzuki, Norio, Chanturiya, Tatyana, Schimel, Daniel, Hugendubler, Lynne, Mammen, Selin, Yver, Dena R., Cushman, Samuel W., Mueller, Elisabetta, Yamamoto, Masayuki, Hsu, Lewis L., Noguchi, Constance Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542973/
https://www.ncbi.nlm.nih.gov/pubmed/22044999
http://dx.doi.org/10.1038/ncomms1526