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The Neuroendocrine Protein 7B2 Suppresses the Aggregation of Neurodegenerative Disease-related Proteins

Neurodegenerative diseases such as Alzheimer (AD) and Parkinson (PD) are characterized by abnormal aggregation of misfolded β-sheet-rich proteins, including amyloid-β (Aβ)-derived peptides and tau in AD and α-synuclein in PD. Correct folding and assembly of these proteins are controlled by ubiquitou...

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Detalles Bibliográficos
Autores principales: Helwig, Michael, Hoshino, Akina, Berridge, Casey, Lee, Sang-Nam, Lorenzen, Nikolai, Otzen, Daniel E., Eriksen, Jason L., Lindberg, Iris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542996/
https://www.ncbi.nlm.nih.gov/pubmed/23172224
http://dx.doi.org/10.1074/jbc.M112.417071