KML001 Displays Vascular Disrupting Properties and Irinotecan Combined Antitumor Activities in a Murine Tumor Model

KML001 is sodium metaarsenite, and has shown cytotoxic activity in human tumor cell lines. The anti-cancer mechanism of KML001 involves cancer cell destruction due to DNA damage at the telomeres of cancer cell chromosomes. In this study, we assessed the vascular disrupting properties of KML001 and i...

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Detalles Bibliográficos
Autores principales: Moon, Chang Hoon, Lee, Seung Ju, Lee, Ho Yong, Lee, Jong Cheol, Cha, HeeJeong, Cho, Wha Ja, Park, Jeong Woo, Park, Hyun Jin, Seo, Jin, Lee, Young Han, Song, Ho-Taek, Min, Young Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543270/
https://www.ncbi.nlm.nih.gov/pubmed/23326531
http://dx.doi.org/10.1371/journal.pone.0053900

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543270/
https://www.ncbi.nlm.nih.gov/pubmed/23326531
http://dx.doi.org/10.1371/journal.pone.0053900

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