Network-based assessment of the selectivity of metabolic drug targets in Plasmodium falciparum with respect to human liver metabolism

BACKGROUND: The search for new drug targets for antibiotics against Plasmodium falciparum, a major cause of human deaths, is a pressing scientific issue, as multiple resistance strains spread rapidly. Metabolic network-based analyses may help to identify those parasite’s essential enzymes whose homo...

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Detalles Bibliográficos
Autores principales: Bazzani, Susanna, Hoppe, Andreas, Holzhütter, Hermann-Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543272/
https://www.ncbi.nlm.nih.gov/pubmed/22937810
http://dx.doi.org/10.1186/1752-0509-6-118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543272/
https://www.ncbi.nlm.nih.gov/pubmed/22937810
http://dx.doi.org/10.1186/1752-0509-6-118

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