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Continuing Exposure to Low-Dose Nonylphenol Aggravates Adenine-Induced Chronic Renal Dysfunction and Role of Rosuvastatin Therapy

BACKGROUND: Nonylphenol (NP), an environmental organic compound, has been demonstrated to enhance reactive-oxygen species (ROS) synthesis. Chronic exposure to low-dose adenine (AD) has been reported to induce chronic kidney disease (CKD). METHODS: In this study, we tested the hypothesis that chronic...

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Detalles Bibliográficos
Autores principales: Yen, Chia-Hung, Sun, Cheuk-Kwan, Leu, Steve, Wallace, Christopher Glenn, Lin, Yu-Chun, Chang, Li-Teh, Chen, Yung-Lung, Tsa, Tzu-Hsien, Kao, Ying-Hsien, Shao, Pei-Lin, Hsieh, Chi-Ying, Chen, Yen-Ta, Yip, Hon-Kan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543300/
https://www.ncbi.nlm.nih.gov/pubmed/22812704
http://dx.doi.org/10.1186/1479-5876-10-147