Pharmacological Inhibition of mTORC1 Prevents Over-Activation of the Primordial Follicle Pool in Response to Elevated PI3K Signaling

The majority of ovarian primordial follicles must be preserved in a quiescent state to allow for the regular production of gametes over the female reproductive lifespan. However, the molecular mechanism that maintains the long quiescence of primordial follicles is poorly understood. Under certain pa...

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Detalles Bibliográficos
Autores principales: Adhikari, Deepak, Risal, Sanjiv, Liu, Kui, Shen, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543305/
https://www.ncbi.nlm.nih.gov/pubmed/23326514
http://dx.doi.org/10.1371/journal.pone.0053810

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543305/
https://www.ncbi.nlm.nih.gov/pubmed/23326514
http://dx.doi.org/10.1371/journal.pone.0053810

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