The Developmental Regulator Pax6 Is Essential for Maintenance of Islet Cell Function in the Adult Mouse Pancreas

The transcription factor Pax6 is a developmental regulator with a crucial role in development of the eye, brain, and olfactory system. Pax6 is also required for correct development of the endocrine pancreas and specification of hormone producing endocrine cell types. Glucagon-producing cells are alm...

Descripción completa

Detalles Bibliográficos
Autores principales: Hart, Alan W., Mella, Sebastien, Mendrychowski, Jacek, van Heyningen, Veronica, Kleinjan, Dirk A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543312/
https://www.ncbi.nlm.nih.gov/pubmed/23326594
http://dx.doi.org/10.1371/journal.pone.0054173

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543312/
https://www.ncbi.nlm.nih.gov/pubmed/23326594
http://dx.doi.org/10.1371/journal.pone.0054173

Ejemplares similares