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PDLIM2 restricts Th1 and Th17 differentiation and prevents autoimmune disease

BACKGROUND: PDLIM2 is essential for the termination of the inflammatory transcription factors NF-κB and STAT but is dispensable for the development of immune cells and immune tissues/organs. Currently, it remains unknown whether and how PDLIM2 is involved in physiologic and pathogenic processes. RES...

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Detalles Bibliográficos
Autores principales: Qu, Zhaoxia, Fu, Jing, Ma, Huihui, Zhou, Jingjiao, Jin, Meihua, Mapara, Markus Y, Grusby, Michael J, Xiao, Gutian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543335/
https://www.ncbi.nlm.nih.gov/pubmed/22731402
http://dx.doi.org/10.1186/2045-3701-2-23