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Pandemic influenza A virus codon usage revisited: biases, adaptation and implications for vaccine strain development

BACKGROUND: Influenza A virus (IAV) is a member of the family Orthomyxoviridae and contains eight segments of a single-stranded RNA genome with negative polarity. The first influenza pandemic of this century was declared in April of 2009, with the emergence of a novel H1N1 IAV strain (H1N1pdm) in Me...

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Detalles Bibliográficos
Autores principales: Goñi, Natalia, Iriarte, Andrés, Comas, Victoria, Soñora, Martín, Moreno, Pilar, Moratorio, Gonzalo, Musto, Héctor, Cristina, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543350/
https://www.ncbi.nlm.nih.gov/pubmed/23134595
http://dx.doi.org/10.1186/1743-422X-9-263