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Sox2 Is an Androgen Receptor-Repressed Gene That Promotes Castration-Resistant Prostate Cancer

Despite advances in detection and therapy, castration-resistant prostate cancer continues to be a major clinical problem. The aberrant activity of stem cell pathways, and their regulation by the Androgen Receptor (AR), has the potential to provide insight into novel mechanisms and pathways to preven...

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Detalles Bibliográficos
Autores principales: Kregel, Steven, Kiriluk, Kyle J., Rosen, Alex M., Cai, Yi, Reyes, Edwin E., Otto, Kristen B., Tom, Westin, Paner, Gladell P., Szmulewitz, Russell Z., Vander Griend, Donald J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543364/
https://www.ncbi.nlm.nih.gov/pubmed/23326489
http://dx.doi.org/10.1371/journal.pone.0053701