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SUMOylation Is Required for Glycine-Induced Increases in AMPA Receptor Surface Expression (ChemLTP) in Hippocampal Neurons

Multiple pathways participate in the AMPA receptor trafficking that underlies long-term potentiation (LTP) of synaptic transmission. Here we demonstrate that protein SUMOylation is required for insertion of the GluA1 AMPAR subunit following transient glycine-evoked increase in AMPA receptor surface...

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Detalles Bibliográficos
Autores principales: Jaafari, Nadia, Konopacki, Filip A., Owen, Thomas F., Kantamneni, Sriharsha, Rubin, Philip, Craig, Tim J., Wilkinson, Kevin A., Henley, Jeremy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543417/
https://www.ncbi.nlm.nih.gov/pubmed/23326329
http://dx.doi.org/10.1371/journal.pone.0052345