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Structure-Activity Relationships of the Antimicrobial Peptide Arasin 1 — And Mode of Action Studies of the N-Terminal, Proline-Rich Region

Arasin 1 is a 37 amino acid long proline-rich antimicrobial peptide isolated from the spider crab, Hyas araneus. In this work the active region of arasin 1 was identified through structure-activity studies using different peptide fragments derived from the arasin 1 sequence. The pharmacophore was fo...

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Detalles Bibliográficos
Autores principales: Paulsen, Victoria S., Blencke, Hans-Matti, Benincasa, Monica, Haug, Tor, Eksteen, Jacobus J., Styrvold, Olaf B., Scocchi, Marco, Stensvåg, Klara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543460/
https://www.ncbi.nlm.nih.gov/pubmed/23326415
http://dx.doi.org/10.1371/journal.pone.0053326