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Identity-by-descent-based heritability analysis in the Northern Finland Birth Cohort

For most complex traits, only a small proportion of heritability is explained by statistically significant associations from genome-wide association studies (GWAS). In order to determine how much heritability can potentially be explained through larger GWAS, several different approaches for estimati...

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Detalles Bibliográficos
Autores principales: Browning, Sharon R., Browning, Brian L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543768/
https://www.ncbi.nlm.nih.gov/pubmed/23052944
http://dx.doi.org/10.1007/s00439-012-1230-y