Triptolide Transcriptionally Represses HER2 in Ovarian Cancer Cells by Targeting NF-κB

Triptolide (TPL) inhibits the proliferation of a variety of cancer cells and has been proposed as an effective anticancer agent. In this study, we demonstrate that TPL downregulates HER2 protein expression in oral, ovarian, and breast cancer cells. It suppresses HER2 protein expression in a dose- an...

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Detalles Bibliográficos
Autores principales: Ou, Chien-Chih, Chen, Yuan-Wu, Hsu, Shih-Chung, Sytwu, Huey-Kang, Loh, Shih-Hurng, Li, Jhy-Wei, Liu, Jah-Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543825/
https://www.ncbi.nlm.nih.gov/pubmed/23346199
http://dx.doi.org/10.1155/2012/350239

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543825/
https://www.ncbi.nlm.nih.gov/pubmed/23346199
http://dx.doi.org/10.1155/2012/350239

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