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Survivin selective inhibitor YM155 induce apoptosis in SK-NEP-1 Wilms tumor cells
BACKGROUND: Survivin, a member of the family of inhibitor of apoptosis proteins, functions as a key regulator of mitosis and programmed cell death. YM155, a novel molecular targeted agent, suppresses survivin, which is overexpressed in many tumor types. The aim of this study was to determine the ant...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543843/ https://www.ncbi.nlm.nih.gov/pubmed/23267699 http://dx.doi.org/10.1186/1471-2407-12-619 |